Leah Bressler

Screen-Shot-2015-10-07-at-1.09.32-PM

Dr. Amander Clark of UCLA reviewed how differentiation of germ cells can be achieved from induced pluripotent stem cells (IPS). She reviewed how cells from the inner cell mass develop into the epiblast, which develop into all somatic cells including the primordial germ cell which differentiates into oogonia-> oocytes. Studies in their laboratory demonstrate that day 3 primordial germ cell-like cells (PGCLCs) in reconstituted ovaries can initiate meiosis. She then reviewed their procedure for identifying human primordial germ cells and outlined the next frontier: differentiating human primordial germ cells into oogonia.

Add new comment

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.